Is dexamethasone available in South Africa?
As highlighted by the patient leaflet on Medicines.org, the manufacturer included is Aspen Bad Oldesloe GmbH, 32-36 Industriestrasse, 23843 Bad Oldesloe, Germany. Although, there are …
Why invest in dexamethasone stock?
Jun 17, 2020 · It is confirmed that Aspen owns rights to this product and distributes both injectables and/or tablets containing dexamethasone in a number of countries. Aspen markets an injectable dexamethasone in South Africa, which is manufactured locally by a third party.
Is dexamethasone made by Merck?
Zydus Cadila is a leading manufacturer of liquid and tablet dexamethasone, owning an 83% market share in the drug and having ample supply for worldwide usage.
Who is the largest dexamethasone producer in Brazil?
Jun 19, 2020 · This will help you decide if it’s time to invest in dexamethasone stock. Recruitment for the trial began on June 8. There were more than 11,500 patients, but only 2,104 were treated with dexamethasone. Patients received the dexamethasone either by mouth or by intravenous injection. They took a total of six milligrams (mg) a day for 10 days total.
Who makes dexamethasone in Brazil?
Aché Laboratórios is the largest producer of dexamethasone in Brazil and is the owner of 357 brands and 142 therapeutic classes in prescription, OTC, generic, and specialty care drugs.
What is dexamethasone used for?
Dexamethasone is used to treat diseases of inflammation such as arthritis , immune system disorders , allergic reactions, colitis, asthma, and even certain types of cancer, all of which involve dysregulation of immune and inflammatory responses.
What is the name of the hormone that is pronounced "dexamethasone"?
Dexamethasone (pronounced dex-ah-meth-ah-zone) is a corticosteroid hormone drug – this sounds technical, but we will break down these two words to reveal what this drug is, and how it works. Let’s start with the second word: When someone says “hormone”, names like testosterone and estrogen come to mind.
What is Merck and Co?
is one of the largest pharmaceutical companies in the world, producing vaccines, numerous brand name and generic medications, and various other healthcare solutions. They originally made dexamethasone in 1958 under their brand Decadron, and still manufacture biosimilar products in oral, IV, and topical forms.
Where is Fera Pharmaceuticals located?
Fera partners with eye care specialists, experts, and emerging pharmaceutical companies to produce drug solutions. They are based out of Locust Valley, NY .
Is dexamethasone dangerous?
Dexamethasone and COVID-19: the RECOVERY trial. COVID-19 is a dangerous virus for many reasons, but one of the most dangerous aspects of it is its ability to cause hyperactivity of the immune response in vital organs such as the lungs, leading to tissue damage .
Is dexamethasone a reliable drug?
Dexamethasone has been around for decades, meaning it has been rigorously tested and implemented in medicine and is considered a reliable, low-risk medication.
How much is dexamethasone?
Dexamethasone is inexpensive. In the United States a month of medication is typically priced less than US$25. In India, a course of treatment for preterm labor is about US$0.50. The drug is available in most areas of the world.
When was dexamethasone first used?
Dexamethasone was first synthesized in 1957 by Philip Showalter Hench and was approved for medical use in 1961. It is on the World Health Organization's List of Essential Medicines. In 2017, it was the 321st most commonly prescribed medication in the United States, with more than one million prescriptions.
Why is dexamethasone given to women?
Dexamethasone may be given to women at risk of delivering prematurely to promote maturation of the fetus' lungs. This administration, given from one day to one week before delivery, has been associated with low birth weight, although not with increased rates of neonatal death.
How long does dexamethasone last?
The effects of dexamethasone are frequently seen within a day and last for about three days.
Why is dexamethasone used in cardiac pacing?
Dexamethasone is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium. The steroid is released into the myocardium as soon as the screw is extended and can play a significant role in minimizing the acute pacing threshold due to the reduction of inflammatory response.
What is the CAS number for dexamethasone?
Combined with marbofloxacin and clotrimazole, dexamethasone is available under the name Aurizon, CAS number 115550-35-1, and used to treat difficult ear infections, especially in dogs. It can also be combined with trichlormethiazide to treat horses with swelling of distal limbs and general bruising.
Which is more effective, dexamethasone or ondansetron?
The combination of dexamethasone and a 5-HT 3 receptor antagonist such as ondansetron is more effective than a 5-HT 3 receptor antagonist alone in preventing postoperative nausea and vomiting.
Why Invest in Dexamethasone Stock?
There aren’t many companies that produce dexamethasone. But it’s important to break down the study before going any further. This will help you decide if it’s time to invest in dexamethasone stock.
Can You Buy Dexamethasone Stock?
This breakthrough may be the biggest yet. So you can expect the stock market to respond quickly. Can you invest in dexamethasone stock today?
Biotech Stocks Are Booming
Dexamethasone isn’t the first drug to make an impact in the fight against coronavirus, and it certainly won’t be the last. It’s important to consider a wide range of biotech companies for your portfolio.
Overview
Dexamethasone is a glucocorticoid medication used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), and along with antibiotics in tuberculosis. In adrenocortical insufficiency, it may be used in combination wit…
Medical uses
Dexamethasone is used to treat many inflammatory and autoimmune disorders, such as rheumatoid arthritis and bronchospasm. Idiopathic thrombocytopenic purpura, a decrease in numbers of plateletsdue to an immune problem, responds to 40 mg daily for four days; it may be administered in 14-day cycles. It is unclear whether dexamethasone in this condition is significantly better than …
Contraindications
Contraindications of dexamethasone include, but are not limited to:
• Uncontrolled infections
• Known hypersensitivity to dexamethasone
• Cerebral malaria
• Systemic fungal infection
Adverse effects
The exact incidence of the adverse effects of dexamethasone are not available, hence estimates have been made as to the incidence of the adverse effects below based on the adverse effects of related corticosteroids and on available documentation on dexamethasone.
• Acne
• Amnesia
Interactions
Known drug interactions include:
• Inducers of hepatic microsomal enzymes such as barbiturates, phenytoin, and rifampicin can reduce the half-life of dexamethasone.
• Cotreatment with oral contraceptives can increase its volume of distribution.
Pharmacology
As a glucocorticoid, dexamethasone is an agonist of the glucocorticoid receptor (GR). It has minimal mineralocorticoid activity.
Chemistry
Dexamethasone is a synthetic pregnane corticosteroid and derivative of cortisol (hydrocortisone) and is also known as 1-dehydro-9α-fluoro-16α-methylhydrocortisone or as 9α-fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione. The molecular and crystal structure of dexamethasone has been determined by X-ray crystallography. It is a stereoisomer of betamethasone, …
History
Dexamethasone was first synthesized by Philip Showalter Hench in 1957. It was introduced for medical use in 1958.
On 16 June 2020, the RECOVERY Trial announced preliminary results stating that dexamethasone improves survival rates of hospitalized patients with COVID‑19 receiving oxygen or on a ventilator. Benefits were only observed in patients requiring respiratory support; those who did not require …