
What is the definition of at?
Definition of at (Entry 1 of 7) 1 —used as a function word to indicate presence or occurrence in, on, or near staying at a hotel at a party sick at heart 2 —used as a function word to indicate …
What does dated at mean on a document?
What is assistive technology? Assistive technology (AT) is any item, piece of equipment, software program, or product system that is used to increase, maintain, or improve the functional capabilities of persons with disabilities. AT can be low-tech: communication boards made of cardboard or fuzzy felt.
What does at what cost mean?
Apr 12, 2021 · 1. Short for advanced technology, AT is an IBM computer first introduced in 1984. The base model AT computer contained an 80286 processor, 256 k of RAM and a 1.2 MB floppy disk drive. The AT was also available with 512 k of RAM and a 20 Mbyte disk drive. Today, an AT-class system is any computer with a 16-bit, 32-bit, or 64-bit system.
What does the term 'at least' mean in math?
Ataxia-telangiectasia, or “A-T,” is a progressive, degenerative disease that affects a startling variety of body systems. The first signs of the disease usually appear early in childhood (the toddler stage), when children begin to walk. Though they usually start walking at a normal age, they wobble or sway when walking, standing still or ...

What is the AT gene?
The A-T gene It is a large gene on chromosome 11 that comprises more than 150,000 bases of DNA and is organized in 66 segments (exons) that contain the information for the structure of its product, the ATM protein. Mutations have been found in all parts of the ATM gene in the DNA of A-T patients.
What is ataxia-telangiectasia syndrome?
Ataxia-telangiectasia (AT) is a rare inherited condition that affects the nervous system, the immune system and other body systems. It is characterized by the presence of: Progressive ataxia (lack of coordination) due to a defect in the cerebellum (the part of the brain involved in coordinating the movement of muscles)
What does ataxia-telangiectasia do to the immune system?
People with ataxia-telangiectasia often have a weakened immune system, and many develop chronic lung infections. They also have an increased risk of developing cancer, particularly cancer of blood-forming cells (leukemia ) and cancer of immune system cells (lymphoma ).
What's another name for ataxia-telangiectasia?
Ataxia telangiectasia (A-T), also known as Louis-Bar syndrome, is a rare genetic form of early-onset autosomal recessive ataxia. The clinical picture is characterized by a combination of neurological and systemic symptoms due to the mutation of the ataxia telangiectasia mutated (ATM) gene.Feb 4, 2022
How is at inherited?
How is A-T inherited? Normally, every cell has 2 copies of each gene: 1 inherited from the mother and 1 inherited from the father. A-T follows an autosomal recessive inheritance pattern. In autosomal recessive inheritance, a mutation must be present in both copies of the gene in order for a person to be affected.
How is AT diagnosed?
A diagnosis of ataxia telangiectasia is made based upon a detailed patient history, a thorough clinical evaluation, identification of characteristic symptoms, and a variety of specialized tests including blood tests, magnetic resonance imaging (MRI), and karyotyping.
How long can you live with ataxia-telangiectasia?
Ataxia telangiectasia is a rare, multiorgan neurodegenera- tive disorder with enhanced vulnerability to cancer and infection. Median survival in two large cohorts of patients with this disease, one prospective and one retrospective, is 25 and 19 years, with a wide range.
How do you prevent ataxia-telangiectasia?
PreventionPhysical Therapy. Studies show that the single most important supportive therapy for A-T patients is aggressive physical therapy (Spacey et al. ... Intravenous Immunoglobulin (IVIG) Treatment. ... Radiation Avoidance. ... Breast Cancer Screening.
Can ataxia cause hair loss?
The research team concluded that Friedreich's ataxia patients experience ultra-structural alterations in their hairs and suggest that this might be due to the oxidative stress that is caused by deficient frataxin expression in the mitochondria.Jul 7, 2015
Is Friedreich's ataxia terminal?
About 15 to 20 years after symptoms emerge, many people with Friedreich's ataxia have to rely on a wheelchair. Those who have advanced ataxia might not be able to get around at all. Heart disease is the leading cause of death among people with Friedreich's ataxia. It usually becomes fatal by early adulthood.
What does the ATM gene do?
The ATM gene provides instructions for making a protein that is located primarily in the nucleus of cells, where it helps control the rate at which cells grow and divide.
What does "at" mean in the dictionary?
Idioms about at. be at (someone), to be sexually aggressive toward (a person): She's pregnant again because he's at her morning, noon, and night. where it's at, Informal. the place where the most interesting or exciting things happen: Emma says that Rome is definitely where it's at now.
What is 23andme at home?
The at -home genetics testing company 23andme, established in 2006, helps people learn more about their “DNA rel at ives.”. This at -home blood test kit gives a full reading of antioxidant, f at ty acid, or vitamin panels. At -home caretakers are eligible for Medicaid waivers, which allow benefits regardless of income.
What is AT in computer terms?
AT can be high-tech: special-purpose computers. AT can be hardware: prosthetics, mounting systems, and positioning devices. AT can be computer hardware: special switches, keyboards, and pointing devices. AT can be computer software: screen readers and communication programs.
What is AT in education?
AT can be inclusive or specialized learning materials and curriculum aids. AT can be specialized curricular software. AT can be much more—electronic devices, wheelchairs, walkers, braces, educational software, power lifts, pencil holders, eye-gaze and head trackers, and much more. Assistive technology helps people who have difficulty speaking, ...
What is the ATIA conference?
The ATIA Conference, held annually since 1999, showcases products and services for the assistive technology community—from users to educators to industry and government professionals. In addition, the ATIA sponsors working groups through which its members work to advance industry standards as technology changes, ...
What is an ATIA?
The ATIA is a not-for profit membership organization of manufacturers, sellers, and providers of technology-based assistive devices and services. ATIA members are active in providing assistive technology for the gamut of disabilities: Autism spectrum disorders. Blindness and low vision. Deafness and hard of hearing.
What is an assistive technology?
Assistive technology (AT) is any item, piece of equipment, software program, or product system that is used to increase, maintain, or improve the functional capabilities of persons with disabilities. AT can be low-tech: communication boards made of cardboard or fuzzy felt. AT can be high-tech: special-purpose computers.
What is an AT computer?
1. Short for advanced technology, AT is an IBM computer first introduced in 1984. The base model AT computer contained an 80286 processor, 256 k of RAM and a 1.2 MB floppy disk drive. The AT was also available with 512 k of RAM and a 20 Mbyte disk drive. Today, an AT-class system is any computer with a 16-bit, 32-bit, or 64-bit system.
What is AT class?
Today, an AT-class system is any computer with a 16-bit, 32-bit, or 64-bit system. Earlier computers (8-bit) were known as PC/XT-class systems. All new computers used today are considered AT-class computers and you're not likely to encounter earlier computers.
How to make the @ symbol on a keyboard?
Creating the @ symbol on a U.S. keyboard. To create the at symbol using a U.S. PC keyboard, hold down the Shift and press the number 2 near the top of the keyboard. To create the at symbol using an Apple keyboard, hold down the Option key and press the number 2 at the top of the keyboard.
What is A-T in medical terms?
Ataxia-telangiectasia, or “A-T,” is a progressive, degenerative disease that affects a startling variety of body systems. The first signs of the disease usually appear early in childhood (the toddler stage), when children begin to walk. Though they usually start walking at a normal age, they wobble or sway when walking, standing still or sitting.
How common is A-T?
Epidemiologists estimate the frequency of A-T between 1 in 40,000 and 1 in 100,000 births. But it is believed that many children with A-T, particularly those who die at a young age, are never properly diagnosed. Therefore, this disease may actually be much more common.
What are the other features of A-T?
Other features of ataxia-telangiectasia that may affect some children are: diabetes mellitus, premature graying of the hair, difficulty swallowing causing choking and/or drooling and slowed growth. Even though A-T is a multi-system disorder, most individuals with A-T are very socially aware and socially skilled.
Why do children with A-T lose their ability to write?
Because of the worsening ataxia, children with A-T lose their ability to write, and speech also becomes slowed and slurred. Even reading eventually becomes impossible as eye movements become difficult to control. Telangiectasia.
Can A-T patients tolerate radiation?
Ironically, another facet of the disease is an extreme sensitivity to radiation, which means that A-T patients cannot tolerate the standard levels of therapeutic radiation or radiomimetic drugs (chemotherapy drugs that work in a way that is similar to radiation therapy) usually given to cancer patients. Other Features of A-T.
Can A-T cause pneumonia?
For these A-T patients, the combination of a weakened immune system and the progressive ataxia can ultimately lead to pneumonia as a common cause of death. Predisposition to Cancer. Children with A-T tend to develop malignancies of the blood system almost 1,000 times more frequently than the general population.
Is A-T incurable?
A-T is presently incurable and unrelenting. If they are lucky enough not to develop cancer, most A-T children are dependent on wheelchairs by the age of ten, not because their muscles are too weak, but because they cannot control them. Later, A-T patients usually die from respiratory failure or cancer by their early or mid-twenties.
When to use "at" or "at"?
The preposition 'at' is used with specific times of the day. This includes any exact hours with 'o'clock' — at one o'clock, five o'clock, etc. For more specific times, use the numbers. Generally, we use the twelve-hour clock when speaking about everyday life. Schedules use the twenty-four clock.
What is the preposition for "at"?
The preposition 'at' is used when referring to buildings as locations in a city. This can be confused with the preposition 'in'. Generally, 'in' is used with buildings to mean that something occurs inside the building. 'At', on the other hand, is used to express that something happens at the location.
What does "at any rate" mean?
'At any rate' often begins an informal sentence to move the discussion from one topic to another, or to end a story. 'At any rate' can also finish a sentence.
When to use "in" in a sentence?
If you are careful you can see Venus on the horizon at sunrise. Jeremy often goes to be late at night. Use 'in' when referring to a period of time in the future. We will be finished with the project in two weeks' time. I think I'm going to study Russian in three years.
What is the most common preposition in English?
Updated July 12, 2019. 'At' is one of the most common prepositions in English. The preposition 'at' is also used in a number of set phrases. This page summarizes the preposition 'at' used for time and place using examples to illustrate usage. Important prepositional phrases with 'an' are used as discourse markers which help connect sentences.
Is AT&T stock down?
AT&T stock was down over 26% in 2020, even after recovering nearly 30% from its lows of the coronavirus bear market. So far in 2021, share have traded down 2%. On the positive side, the stock maintains a high 7.4% annualized dividend yield in a very low interest rate environment.
Is the stock market in an uptrend?
Currently, the stock market is in an uptrend which means it's a great time to identify top stock contenders for your portfolio and initiate new positions. Investors should seek out leading stocks in leading industry groups that are outperforming the market.
